A central debate in philosophy and neuroscience pertains to whether PFC activity plays an essential role in the neural basis of consciousness. Neuroimaging and electrophysiology studies have revealed that the contents of conscious perceptual experience can be successfully decoded from PFC activity, but these findings might be confounded by post- perceptual cognitive processes, such as thinking, reasoning, and decision-making, that are not necessary for con- sciousness. To clarify the involvement of the PFC in consciousness, we present a synthesis of research (...) that has used intracranial electrical stimulation (iES) for the causal modulation of neural activity in the human PFC. This research provides compelling evidence that iES of only certain prefrontal regions (i.e., orbitofrontal cortex and anterior cingu- late cortex) reliably perturbs conscious experience. Conversely, stimulation of anterolateral prefrontal sites, often con- sidered crucial in higher-order and global workspace theories of consciousness, seldom elicits any reportable alterations in consciousness. Furthermore, the wide variety of iES-elicited effects in the PFC (e.g., emotions, thoughts, and olfactory and visual hallucinations) exhibits no clear relation to the immediate environment. Therefore, there is no evidence for the kinds of alterations in ongoing perceptual experience that would be predicted by higher-order or global workspace theories. Nevertheless, effects in the orbitofrontal and anterior cingulate cortices suggest a specific role for these PFC subregions in supporting emotional aspects of conscious experience. Overall, this evidence presents a challenge for higher-order and global workspace theories, which commonly point to the PFC as the basis for con- scious perception based on correlative and possibly confounded information. (shrink)

An often-overlooked characteristic of the human mind is its propensity to wander. Despite growing interest in the science of mind-wandering, most studies operationalize mind-wandering by its task-unrelated contents. But these contents may be orthogonal to the processes that determine how thoughts unfold over time, remaining stable or wandering from one topic to another. In this chapter, we emphasize the importance of incorporating such processes into current definitions of mind-wandering, and propose that mind-wandering and other forms of spontaneous thought (such as (...) dreaming and creativity) are mental states that arise and transition relatively freely due to an absence of constraints on cognition. We review existing psychological, philosophical and neuroscientific research on spontaneous thought through the lens of this framework, and call for additional research into the dynamic properties of the mind and brain. (shrink)

El debate que se gestó alrededor del concepto de existencia en manos de Willard Van Orman Quine y Rudolf Carnap, dio al siglo XX un cúmulo de aportes significativos a la ontología. La postura realista, con algunas variantes, de Quine y el criterio anti-realista de Carnap, otorga insumos para pensar de mejor forma cómo se intenta dar descripciones acerca del inmobiliario del mundo. Conocer este debate es importante, ya que, se expone los alcances y limitaciones que implican las explicaciones ontológicas (...) acerca de la realidad que deben ser tenidas en cuenta en la actualidad. Este trabajo cumple esa función, la de explicar sintéticamente uno de los debates más importantes para la ontología. (shrink)

In “Harmful Choices, the Case of C, and Decision-Making Competence,” Pickering and colleagues advance an argument in favor of externalism, a view in which the competence of a decision maker is judged relative to factors external to their cognition. In advancing this argument, Pickering and colleagues focus on the external factor of harm: In their view, it is the harmfulness of a considered or chosen action that provides evidence against the competence of the decision maker. However, the proper identification of (...) harmful choices and outcomes remains a demanding task, largely because our understanding of what harm is remains deeply incomplete. Despite 50 years of tempestuous debate, the metaphysics of harm remains an unsettled question. The existence of such a debate does not, in and of itself, provide evidence against the externalist position; rather, it is the theories of harm themselves that pose meaningful challenges for the externalist. Our purpose, here, is to illuminate these challenges. (shrink)

Ce texte est le fruit d’une collaboration entre un astrophysicien, Jean-René Roy, et un philosophe de l’éducation, Normand Baillargeon. Ils ont en commun d’avoir été marqués par la fréquentation des oeuvres de Mario Bunge, auxquelles ils attachent un grand prix, sur un plan personnel, d’abord, mais aussi, et c’est ce qu’ils veulent rappeler dans ces pages : parce qu’ils estiment que les oeuvres de Bunge contribuent de manière extrêmement forte et positive à rendre plus salubre la vie de l’esprit, en (...) enrichissant notre intellect et en luttant contre diverses formes troublantes d’obscurantisme qui y sévissent parfois, notamment dans les domaines familiers aux deux auteurs. (shrink)

The precautionary principle in public decision making concerns situations where following an assessment of the available scientific information, there are reasonable grounds for concern for the possibility of adverse effects on the environment or human health, but scientific uncertainty persists. In such cases provisional risk management measures may be adopted, without having to wait until the reality and seriousness of those adverse effects become fully apparent. This is the definition of the precautionary principle as operationalized under EU law. The precautionary (...) principle is a deliberative principle. Its application involves deliberation on a range of normative dimensions which need to be taken into account while making the principle operational in the public policy context. Under EU law, any risk management measures to be adopted while implementing the precautionary principle, have to be proportionate to ensure the chosen high level of protection in the European Community. This articlewill illustrate the established practice concerning the release of genetically modified organisms into the environment and how the principle is implemented under hard law. The article also provides an outlook on what this may imply for the relative new case of nanotechnology and the use of precautionary principle within the context of soft law (use of codes of conduct). (shrink)

Descartes was born in La Haye (now Descartes) in Touraine and educated at the Jesuit college of La Fleche` in Anjou. Descartes’modern reputation as a rationalistic armchair philosopher, whose mind–body dualism is the source of damaging divisions between psychology and the life sciences, is almost entirely undeserved. Some 90% of his surviving correspondence is on mathematics and scientific matters, from acoustics and hydrostatics to chemistry and the practical problems of constructing scientific instruments. Descartes was just as interested in the motions (...) of matter as in the supernatural soul, and he advised against spending too much time on metaphysical inquiries which neglect imagination and the senses. After meeting the Dutch engineer Isaac Beeckman in 1618, Descartes became committed to a systematically ‘mechanical’account of nature. This involved explaining all natural processes in terms of interactions between microscopic material bodies in motion. Descartes modelled his physics and cosmology on the behaviour of fluids, which also have a distinctive and central role in his physiology: the key processes for natural philosophical investigation are the circulation and mutual displacement of constrained bodies, rather than the isolated collisions of atoms in a void. Descartes settled in Holland in 1628, and commenced an ambitious programme of physiological research. In 1630 he was ‘studying chemistry and anatomy simultaneously’, and in late 1632 he was ‘dissecting the heads of various animals’, in order to ‘explain what imagination, memory, etc. consist in’. By late 1633 Descartes had almost completed L’homme, the Treatise on Man; but he abandoned plans to publish it along with a work on matter theory and optics which relied on Copernican cosmology, after he heard of the condemnation of Galileo. L’homme was published posthumously in 1662 (Latin) and 1664 (French); not until 1972 was it fully translated into English. L’homme draws on many (mostly unnamed) Renaissance medical writers, and covers, firstly, a range of traditional physiological topics, such as digestion and respiration.. (shrink)

RENÉ DESCARTES: UMA BIOGRAFIA -/- RENÉ DESCARTES: A BIOGRAPHY -/- Emanuel Isaque Cordeiro da Silva - CAP-UFPE, IFPE-BJ e UFRPE. E-mails: [email protected] e [email protected]. WhatsApp: (82)98143-8399. -/- -/- Nascido em 1596 em Haia, nas fronteiras de Touraine e Poitou, em uma família nobre, René Descartes vem ao mundo ao mesmo ano em que Johannes Kepler (1671-1630), em seu primeiro trabalho publicado (Mysterium cosmographicum), prova a superioridade da astronomia moderna (a de Nicolau Copérnico (1473-1543)) da astronomia antiga (a de Ptolomeu (90-168 (...) d.C.)). Ao mesmo tempo, Galileu Galilei (1564-1642), que detém a cadeira de matemática da Universidade de Pádua, funda o método experimental. As descobertas de Galileu tiveram forte impacto sobre o Colégio Real de La Fleche, realizado pelos jesuítas e onde Descartes recebeu, a partir de 1606, uma forte educação. Ele menciona, no Discurso do Método, seu “desejo extremo” em aprender, seguido, no final de seus estudos, de uma grande decepção: decepção com a filosofia ensinada, cujas controvérsias perpétuas revelam um caráter questionável, e que não pode fornecer um alicerce, em seu estado atual, para outras ciências. Também é proferido um desapontamento, mas esse desapontamento é inverso e diz respeito às matemática, capaz de fornecer esse fundamento que a filosofia não confere, mediante sua certeza e evidências, mas sobre o qual ainda não construímos nada. -/- -/- Numa Europa marcada pelo choque do tradicionalismo católico e do mercantilismo protestante, o lento declínio do poder espanhol e a luta dos Países Baixos pela sua independência, Descartes escolheu, primeiramente, após a graduação, a carreira militar. Engajado no exército do Príncipe Maurício de Nassau, ele é retirado da ociosidade da vida da guarnição pelo encontro, em 1618, de um jovem cientista holandês, Isaac Beeckman (1588-1637), que se tornou seu amigo íntimo por algum tempo. Conhecedor de todas as pesquisas científicas do momento e partidário da nova concepção “mecanicista” da natureza, Beeckman compartilhou com Descartes um entusiasmo que foi acompanhado, segundamente, da ambição de realizar a ciência universal por si mesma, mediante um método único: na noite de 10 de novembro de 1619, ele concebe em três “sonhos”, “os alicerces de uma ciência admirável”. -/- Nos anos seguintes a essa iluminação decisiva, Descartes viajou por toda a Europa, estimando, como Michel de Montaigne (1533-1592), que a demonstração de boas maneiras e costumes diferentes podem gerar muitos preconceitos. Toda sua vida, além disso, esteve vagando, isto é, foi marcada por múltiplas mudanças de residências, e a recusa de estabelecer um vínculo muito de perto com alguém. Foi na Holanda que ele, finalmente, buscará a tranquilidade que não encontrara na França ainda abalada pelas guerras religiosas, antes de ser assim pelas convulsões da Fronda. Todavia, mesmo na Holanda, ele não pôde evitar os ataques de calvinistas e polemicas teológicas que o repugnaram, como evidenciado em suas discussões com a Universidade de Utrecht entre 1643 à 1645 e a Universidade de Leiden em 1647. -/- -/- Além de sua amizade com Beeckman, outro encontro teve uma influência indubitavelmente decisiva sobre o destino de Descartes: o encontro com o cardeal de Bérulle. Fundador da congregação do Oratório (ao qual pertencem Nicolas Malebranche (1638-1715) e Jean-Baptiste Massillon (1663-1742)), o cardeal de Bérulle enxerga na nova física mecanicista, um meio de lutar contra o naturalismo resultante do Renascimento e seu paganismo latente: em uma longa entrevista com Descartes, no outono de 1647, ele fez dessa última uma obrigação de consciência para se dedicar, nesse sentido, à filosofia. -/- Em 1628, Descartes começa a escrever as Regras para a direção do espírito, um tratado inacabado e que não foi publicado durante a vida do autor. Em 1631, desenvolvera a geometria analítica que combina curvas geométricas com equações algébricas. Em 1633 escreveu O Tratado do Homem e preparava-se para publicar O Tratado do Mundo quando a notícia da condenação de Galileu Galilei pelo Santo Ofício (a Inquisição) o deixou receoso e decide, por prudência, não publicar o seu Tratado no qual a tese do movimento da Terra ao redor do Sol é apoiada. Alguns anos depois, foi divulgado em público cultivada de algumas de suas descobertas científicas: além da geometria, a dioptria (a teoria da refração da luz) e meteoros (teoria dos fenômenos atmosféricos luminosos). Esses três tratados aparecem no apêndice do Discurso do Método, e como “ensaios” desse método, em 1637. No século XIX, Victor Cousin (1792-1867) publicou pela primeira vez o Discurso sozinho, sem os ensaios. -/- Então vem a principal obra de Descartes no ramo da metafísica: as seis Meditações, aumentadas pelas objeções dos mais famosos filósofos da época (incluindo Thomas Hobbes (1588-1679), Antoine Arnauld (1612-1694) e Pierre Gassendi (1592-1655)), e as respostas a essas objeções, apareceram em 1641. Ansioso para expor sua filosofia para que pudesse ser ensinada, ele também a caracteriza em forma de manual com os Princípios da Filosofia de 1644. -/- Além dos trabalhos publicados, foi por meio das cartas trocadas com personalidades do mundo erudito que Descartes encontrou a oportunidade de esclarecer vários pontos de sua filosofia. Seus principais correspondentes foram o Prade Marin Mersenne (1588-1648), o Padre Denis Mesland (1615-1672), Pierre Chanut (1601-1662), Claude Clerselier (1614-1684), Christiaan Huygens (1629-1695) e Henry More (1614-1687). A partir de 1643, Descartes sustentou, com a Princesa Isabel da Boêmia (1596-1662), uma correspondência dedicada essencialmente a questões morais, que lhe permitiu a formulação de suas ideias nesse campo: esse esforço conduziu, em 1649, ao tratado das Paixões da alma. -/- Nesse mesmo ano, 1649, a Rainha Cristina da Suécia (1626-1689) o convida para ir a Estocolmo, que ele aceitou após muita hesitação. Recebido com todas as honras, mas forçado a um modo de vida bastantemente distinto daquele que era acostumado, e submetido a um clima do qual não se adequou, ele sucumbiu a pneumonia em fevereiro de 1650. -/- Descartes deixou-nos uma espécie de autobiografia intelectual na primeira parte do Discurso do Método: em seus anos de treinamento, seus entusiasmos e suas decepções. O discurso é, também, o primeiro livro para quem busca compreender o projeto filosófico cartesiano desde sua gênese até sua realização. Existem expostos, o método claro (na segunda parte), mas também a moral (terceira parte), a metafísica (quarta parte) e finalmente a física (quinta e sexta partes). (shrink)

Review of THEO C. MEYERING, Historical Roots of Cognitive Science : The Rise of a Cognitive Theory of Perception from Antiquity to the Nineteenth Century. Boston: Kluwer, xix + 250 pp. $69.00. Examines the author's interpretation of Aristotelian theories of perceptual cognition, early modern theories, and Helmholtz's theory.

Anton Wilhelm Amo (c. 1700 – c. 1750) – born in West Africa, enslaved, and then gifted to the Duke of Braunschweig-Wolfenbüttel – became the first African to earn a Ph.D. in philosophy at a European university. He went on to teach philosophy at the Universities of Halle and Jena. On the 16th of April, 1734, at the University of Wittenberg, he defended his dissertation, De Humanae Mentis Apatheia (On the Impassivity of the Human Mind), in which Amo investigates the (...) logical inconsistencies in René Descartes’ (1596 – 1650) res cogitans (mind) and res extensa (body) distinction and interaction by maintaining that (1) the mind does not sense material things nor does it (2) contain the faculty of sensing. (shrink)

The Catastrophe Theory of Rene Thom and E. C. Zeeman suggests a mathematical interpretation of certain aspects of Hegelian and Marxist dialectics. Specifically, the three 'classical' dialectical principles, (1) the transformation of quantity into quality, (2) the unity and struggle of opposites, and (3) the negation of negation, can be modeled with the seven 'elementary catastrophes' given by Thorn, especially the catastrophes known as the 'cusp' and the 'butterfly'. Far from being empty metaphysics or scholasticism, as critics have argued, the (...) dialectical principles embody genuine insights into a class of phenomena, insights which can now be expressed within a precise mathematical formalism. This fact does not, however, support the claim that these principles, possibly modified or supplemented, constitute the laws of motion for human thought and for natural and social processes or even just the last of these. (shrink)

Feminism and Tradition in Aesthetics takes a fresh look at the history of aesthetics and at current debates within the philosophy of art by exploring the ways in which gender informs notions of art and creativity, evaluation and interpretation, and concepts of aesthetic value. Multiple intellectual traditions have formed this field, and the discussions herein range from consideration of eighteenth century legacies of ideas about taste, beauty, and sublimity to debates about the relevance of postmodern analyses for feminist aesthetics. Forward (...) by Arthur C. Danto, 20 authors include Paul Mattick, Jr., Caroline Korsmeyer, Timothy Gould, Christine Battersby, Mary Devereaux, bell hooks, REnee Lorraine, Trinh T. Minh-ha, Elizabeth Ann Dobie, Adrian Piper, Anita Silvers, Susan Feagin, Mary D. Garrard, Ellen Handler Spitz, Noel Carroll, Joanne Waugh, Joseph Margolis, Rita Felski, and Hilde Hein, as well as Peg Brand's essay, "Revising the Aesthetic-Nonaesthetic Distinction: The Aesthetic Value of Activist Art.". (shrink)

RELAÇÃO E EFEITOS BIOQUÍMICO-NUTRICIONAIS SOBRE OS CISTOS OVARIANOS EM VACAS Emanuel Isaque Cordeiro da Silva Departamento de Agropecuária – IFPE Campus Belo Jardim [email protected] ou [email protected] WhatsApp: (82)98143-8399 11. CISTOS OVÁRICOS Os cistos são cavidades anormais que às vezes possuem conteúdo de fluido biológico, ou podem ser cavidades ocas, com paredes sólidas refratárias à maioria dos compostos endógenos. Formam-se como alterações patológicas das células luteais ou foliculares do estroma ovárico. A presença de cistos altera o ciclo estral e obriga a (...) realização de tratamentos exógenos para remover o mesmo, fazendo com que a atividade cíclica da gônada retome sua normalidade (HATLER, et al. 2006). Alguns fatores de origem nutricional, tanto por deficiência de alguns compostos, como por excesso no fornecimento de outros, têm sido considerados como causas potenciais dos cistos, entre os principais fatores nutricionais podemos citar: 11.1 Fito-toxidade/fitoestrogênios Compostos vegetais, tais como plantas com elevado teor de flavonoides estrogênicos, encontram-se sob a forma de glicosídeos e têm a capacidade para modificar os processos reprodutivos devido à sua semelhança com os núcleos esteroides de hormônios femininos; são substâncias estruturais e funcionalmente semelhantes ao 17-ß-estradiol ou que produz efeitos estrogênicos (MENDOZA, et al. 2001). Pouco se sabe sobre os estrogênios presentes nas plantas e os níveis de fito-toxidade dos mesmos, logo na prática torna-se algo difícil de ser observado e atacado. Porém, a nível laboratorial, caso haja alguma complicação que afete o animal para além das capacidades reprodutivas, um diagnóstico aprofundado é o mais indicado. 11.2 Minerais 11.2.1 Iodo (I) Alimentos com baixo teor de iodo, provocam estros silenciosos nos animais e aumentam a incidência de quistos ováricos. O I é parte da molécula de tiroxina que estimula a produção de ATP na mitocôndria, a deficiência reduz a captação de oxigênio o que determina uma diminuição no metabolismo energético. Na tireoide existe um complexo de proteína-iodo, chamado tiroglobulina, essa molécula é uma glicoproteína. A maioria do I é reduzida a iodo inorgânico no trato gastrointestinal e a sua absorção é imediata. A função principal da tireoide é acumular I e fixá-lo, formando hormônios da tireoide sob o controle da adenohipófise por secreção (TSH). O I é convertido em iodeto no trato intestinal e então é transportado para a tireoide, aqui as células foliculares o prendem com efetividade através de um processo de transporte ativo, contra um gradiente de concentração, estimulado por TSH. Uma vez que as hormonas da tireoide controlam o metabolismo, uma deficiência em I diminui a taxa metabólica do organismo, isso afeta indiretamente a reprodução, uma vez que o funcionamento irregular da tireoide afeta a formação de lipídios, esses necessários para a produção de hormônios esteroides (estrogênios) e estes por sua vez influenciam a síntese das prostaglandinas F2-alfa necessária para o processo de luteólise o que faz com que o corpo lúteo não se rompa, perdure e forme um cisto. O I presente no alimento do animal deve estar presente e obedecer o intervalo de 0,34 a 0,88 mg/kg de MS em todos os alimentos que o animal viera a ingerir, seja forragens ou rações. A forma de suplementação são as mais conhecidas, via volumoso, concentrado, água ou pelo sistema SMI. 11.2.2 Manganês (Mn) Níveis elevados de manganês na dieta levam à depleção da absorção de ferro, bem como de outros minerais necessários para a síntese, metabolismo, ativação de enzimas e absorção de outros minerais. Essas interações com outros minerais e o papel do excesso de manganês na inibição da síntese dos precursores de hormonas necessárias para a reprodução, bem como dos metabolitos gerados durante o desdobramento ruminal são representados de forma indireta. Para além do efeito antagônico com outros minerais e enzimas, níveis elevados de manganês provocam uma alteração na população da flora ruminal, o que prejudica a produção de ácido propiônico e butírico a nível ruminal, tendo um efeito negativo no metabolismo dos lipídios com uma subsequente baixa de energia (derivado do metabolismo graxo diminuído ou inibido) e também da síntese de ácidos graxos. Por esta última razão, ocorre uma diminuição na síntese das hormonas esteroides, as quais, não estando presentes em níveis adequados, geram problemas no ciclo estral, uma vez que estas hormonas são essenciais para a síntese das prostaglandinas (PGF2-α) que são necessários para a lise do corpo lúteo, com sua posterior persistência, terminando na formação de um cisto luteal. Como sempre falado nos capítulos dessa compilação de trabalhos, o composto Mn é mais um mineral imprescindível para a alimentação do animal, manutenção normal dos seus mecanismos fisiológicos e relações com outros minerais. Sua disponibilidade para o animal deve ser de 12 a 50 mg/kg de MS das forragens, ou a mesma quantidade no conteúdo da ração balanceada. É um elemento que pode ser colocado na água para absorção pelos animais ou através da suplementação mineral injetável (SMI). 11.2.3 Sódio (Na) Os sinais de deficiência de Na são inespecíficos, mas os mais expressivos são sobre o crescimento e produção leiteira. Numa diminuição do consumo de Na, o organismo ativa os mecanismos de conservação mediados pela liberação de aldosterona que aumenta a reabsorção a nível dos túmulos renais deste mineral. A deficiência de Na afeta a produção de muco cervical, com consequências como problemas na formação de espermatozoides e aumento das infecções uterinas. Dado que a deficiência de Na é rara, apenas os sintomas clínicos desta deficiência mineral podem ser vagamente descritos é k caso da dificuldade de concepção, distorcias e bezerros fracos ao nascimento, além da inatividade ovárica e maior incidência de retenção de placenta. As causas de tais alterações foram motivo de numerosos estudos com resultados contraditórios, as vacas com deficiência de energia no início da amamentação têm diminuição nas concentrações de hormona luteinizante (LH), isto conclui que a alteração ovárica seria determinada por uma alteração da liberação pulsátil de LH devido a uma deficiência energética aguda. A intensidade e a duração do estro são de importância fundamental para a IA nos bovinos. Ao ocorrer uma deficiência de sódio, aumenta-se a estabilização das membranas celulares impedindo que o corpo lúteo se lise, formando-se um cisto, que continuará com a produção de progesterona, levando, por fim, a um anestro patológico. O sódio é um elemento que deve estar disponível aos animais de forma à vontade, ou seja, esse mineral é combinado com o Cl, fazendo o balanceamento eletrolítico e disponibilizado para os animais pelo conhecido sal. Sua administração, como é em sistema à vontade, não é muito controlada, mas o produtor poderá fornecer as quantidades na mistura alimentar do animal, tendo um maior controle da absorção do mesmo pelos animais. Sendo assim, o Na deve ser fornecido em quantidades que obedeçam 0,10 a 0,18% da MS no caso das forrageiras, ou a mesma quantidade misturada no todo da ração, quantidade essa encontrada por meios de cálculos, ou que já vêm na composição da ração industrial. Estudos apontam que um animal deve ingerir cerca de 50 gramas de NaCl por dia, no caso do sódio estar presente em 39% da composição desse cloreto de sódio. REFERÊNCIAS BIBLIOGRÁFICAS BARRENHO, Gonçalo José Pinheiro. Nutrição e fertilidade em bovinos de leite. 2016. Dissertação de Mestrado. Universidade de Évora. BINDARI, Yugal Raj et al. Effects of nutrition on reproduction-A review. Adv. Appl. Sci. Res, v. 4, n. 1, p. 421-429, 2013. BOLAND, M. P. Efectos nutricionales en la reproducción del ganado. XXXI Jornadas Uruguayas de Buiatría, 2003. CHAMBA OCHOA, Hermógenes René; BENÍTEZ GONZÁLEZ, Edgar Enrique; PESÁNTEZ CAMPOVERDE, Manuel Teodoro. Factores predisponentes para la enfermedad quística ovárica bovina y su efecto en la eficiencia reproductiva. Revista de Medicina Veterinaria, v. 1, n. 35, p. 17-28, 2017. DEHNING, R. Interrelaciones entre nutrición y fertilidad. In: Curso Manejo de la Fertilidad Bovina18-23 May 1987Medellín (Colombia). CICADEP, Bogotá (Colombia) Universidad de La Salle, Medellín (Colombia) Instituto Colombiano Agropecurio, Bogotá (Colombia) Sociedad Alemana de Cooperación Técnica-GTZ (Alemania), 1987. DE LUCA, Leonardo J. Nutrición y fertilidad en el ganado lechero. XXXVI Jornadas Uruguayas de Buiatría, 2008. DIAS, Juliano Cesar et al. Alguns aspectos da interação nutrição-reprodução em bovinos: energia, proteína, minerais e vitaminas. PUBVET, v. 4, p. Art. 738-743, 2010. FERNANDES, C. A. C. et al. Fatores predisponentes para cistos ovarianos em vacas da raça holandesa. Ars Veterinaria, v. 21, n. 2, p. 287-296, 2008. GORDON, Ian. Controlled reproduction in farm animals series. Nova Iorque: CAB International, 1996. HATLER, T. B. et al. Effect of a single injection of progesterone on ovarian follicular cysts in lactating dairy cows. The Veterinary Journal, v. 172, n. 2, p. 329-333, 2006. KESLER, D. J.; GARVERICK, H. A. Ovarian cysts in dairy cattle: a review. Journal of animal science, v. 55, n. 5, p. 1147-1159, 1982. MAAS, John. Relationship between nutrition and reproduction in beef cattle. The Veterinary Clinics of North America. Food Animal Practice, v. 3, n. 3, p. 633-646, 1987. MENDOZA, R. Muñoz et al. Parámetros reproductivos en vacas Holstein alimentadas con alfalfa alta en cumestrol. Archivos de zootecnia, v. 51, n. 195, p. 373-376, 2002. PASA, Camila. Relação reprodução animal e os minerais. Biodiversidade, v. 9, n. 1, 2011. SARTORI, Roberto; GUARDIEIRO, Monique Mendes. Fatores nutricionais associados à reprodução da fêmea bovina. Revista Brasileira de Zootecnia, v. 39, p. 422-432, 2010. SHORT, Robert E.; ADAMS, D. C. Nutritional and hormonal interrelationships in beef cattle reproduction. Canadian Journal of Animal Science, v. 68, n. 1, p. 29-39, 1988. THATCHER, W. W. et al. Strategies for improving fertility in the modern dairy cow. Theriogenology, v. 65, n. 1, p. 30-44, 2006. TEIXEIRA, J. C.; TEIXEIRA, LFAC. Alimentação de bovinos leiteiros. FAEPE, Lavras, 1997. YOSHIOKA, Koji; IWAMURA, Shokichi; KAMOMAE, Hideo. Changes of ovarian structures, plasma LH, FSH, progesterone and estradiol-17β in a cow with ovarian cysts showing spontaneous recovery and relapse. Journal of veterinary medical science, v. 60, n. 2, p. 257-260, 1998. (shrink)

The theoretical biology movement originating in Britain in the early 1930’s and the biosemiotics movement which took off in Europe in the 1980’s have much in common. They are both committed to replacing the neo-Darwinian synthesis, and they have both invoked theories of signs to this end. Yet, while there has been some mutual appreciation and influence, particularly in the cases of Howard Pattee, René Thom, Kalevi Kull, Anton Markoš and Stuart Kauffman, for the most part, these movements have developed (...) independently of each other. Focussing on morphogenesis understood as vegetative semiosis, in this paper I will argue that the ideas of these movements are commensurate. Furthermore, synthesising them would enable us to see life processes as proto-narratives. Doing so will involve synthesising biohermeneutics, Peircian biosemiotics with Waddington’s theoretical biology and Piagetian genetic structuralism, and this, I claim, would strengthen the challenge of these traditions to mainstream biology. At the same time, this should contribute to overcoming the opposition between the sciences and the humanities, developing a broader tradition of Schellingian thought which involves developing the humanities and then demanding of the physical and biological sciences that they are consistent with and can make intelligible the emergence of humans as conceived by the humanities. (shrink)

Töz problemi Antik Çağ’dan bu yana farklı adlandırmalar, farklı yorumlamalar şeklinde tartışılmaktadır. Bu çalışma, modern felsefenin kurucularından ve rasyonalist düşünürler olan René Descartes’ın epistemolojisinde ve Benedictus Spinoza’nın ontolojisinde oldukça ciddi bir öneme sahip olan töz kavramının neye karşılık geldiğini ve ortaya çıkardığı temel problemleri ele almaktadır. Descartes’ın birden fazla tözün olabileceği fikri ile düalist bir töz anlayışı geliştirdiği yerde, Spinoza Descartes’a bir eleştiri olarak tek bir tözün kabulüne dayalı monist bir töz anlayışı geliştirmiştir. Doğal olarak bu çalışma töz kavramına tarihsel (...) bir çerçeve çizerek, Descartes’ın ruh-beden düalizmine dayanan töz anlayışı ile Spinoza’nın Tanrı temelli töz anlayışını karşılaştırmayı amaçlamaktadır. (shrink)

Propositional temporalism is the view that there are temporary propositions: propositions that are true, but not always true. Factual futurism is the view that there are futurist facts: facts that obtain, but that will at some point not obtain. Most A-theoretic views in the philosophy of time are committed both to propositional temporalism and to factual futurism. Mark Richard, Jeffrey King and others have argued that temporary propositions are not fit to be the contents of propositional attitudes, or to be (...) the semantic values of natural language utterances. But these discussions have overlooked another role that the A-theorist’s posits struggle to play: the role of facts in explaining other facts. Focusing on the case of action explanation by reasons, this paper presents the challenge that explanation poses for factual futurism. It then brings that challenge to bear against propositional temporalism and the A-theory more generally. My argument saddles the factual futurist with surprising commitments concerning reasons, facts and explanation. The futurist might accept those commitments and pay the price. The alternative – which I prefer – is to reject factual futurism, and with it the A-theory. (shrink)

Law-enforcement agencies are increasingly able to leverage crime statistics to make risk predictions for particular individuals, employing a form of inference that some condemn as violating the right to be “treated as an individual.” I suggest that the right encodes agents’ entitlement to a fair distribution of the burdens and benefits of the rule of law. Rather than precluding statistical prediction, it requires that citizens be able to anticipate which variables will be used as predictors and act intentionally to avoid (...) them. Furthermore, it condemns reliance on various indexes of distributive injustice, or unchosen properties, as evidence of law-breaking. (shrink)

Many of those working on moral responsibility assume that "once blameworthy, always blameworthy." They believe that blameworthiness is like diamonds: it is forever. We argue that blameworthiness is not forever; rather, it can diminish through time. We begin by showing that the view that blameworthiness is forever is best understood as the claim that personal identity is sufficient for diachronic blameworthiness. We argue that this view should be rejected because it entails that blameworthiness for past action is completely divorced from (...) the distinctive psychological features of the person at the later time. This is because on none of the leading accounts of personal identity does identity require the preservation of any distinctive psychological features, but merely requires some form of continuity. The claim that blameworthiness is forever should therefore be rejected. We then sketch an account of blameworthiness over time, and consider two objections. (shrink)

Following Kripke and Putnam, the received view of chemical kinds has been a microstructuralist one. To be a microstructuralist about chemical kinds is to think that membership in said kinds is conferred by microstructural properties. Recently, the received microstructuralist view has been elaborated and defended, but it has also been attacked on the basis of complexities, both chemical and ontological. Here, I look at which complexities really challenge the microstructuralist view; at how the view itself might be made more complicated (...) in order to accommodate such challenges; and finally, at what this increasingly complicated picture implies for our standard assessment of chemical kindhood—primarily, for the widespread assumption that chemical kinds in general are more neat and tidy than those messy biological ones. _1_ The Received View _2_ A Taxonomy of Chemical Kinds _3_ Atomic Number _4_ H2O, H3O+, OH−, and More _5_ Complicating the Microstructuralist Picture _6_ Concrete and Other Mixtures _7_ Macromolecules, Especially Proteins _8_ Abandoning Sameness of Elemental Composition _9_ Not So Different after All. (shrink)

The New Evil Demon problem has been hotly debated since the case was introduced in the early 1980’s (e.g. Lehrer and Cohen 1983; Cohen 1984), and there seems to be recent increased interest in the topic. In a forthcoming collection of papers on the New Evil Demon problem (Dutant and Dorsch, forthcoming), at least two of the papers, both by prominent epistemologists, attempt to resist the problem by appealing to the distinction between justification and excuses. My primary aim here is (...) to critically evaluate this new excuse maneuver as a response to the New Evil Demon problem. -/- Their response attempts to give us reason to reject the idea that victims of the New Evil Demon have justification for believing as they do. I shall argue that this approach is ultimately unsuccessful, however much of value can be learned from these attempts. In particular, progress in the debate can be made by following those who advance the excuse maneuver and make explicit the connection between epistemic justification and epistemic norms. By doing so, the questions being debated are clarified, as is the methodology being used to attempt to answer them. (shrink)

There is a New Idea in epistemology. It goes by the name of ‘knowledge first,’ and it is particularly associated with Timothy Williamson’s book Knowledge and Its Limits. In slogan form, to put knowledge first is to treat knowledge as basic or fundamental, and to explain other states—belief, justification, maybe even content itself—in terms of knowledge, instead of vice versa. The idea has proven enormously interesting, and equally controversial. But deep foundational questions about its actual content remain relatively unexplored. We (...) think that a wide variety of views travel under the banner of ‘knowledge first’ (and that the slogan doesn’t help much with differentiating them). Furthermore, we think it is far from straightforward to draw connections between certain of these views; they are more independent than they are often assumed to be. Our project here is exploratory and clarificatory. We mean to tease apart various ‘knowledge first’ claims, and explore what connections they do or do not have with one another. Our taxonomy is offered in §2, and connections are explored in §3. The result, we hope, will be a clearer understanding of just what the knowledge first theses are. We conclude, in §4, with some brief suggestions as to how we think the various theses might be evaluated. (shrink)

Leuridan (2011) questions whether mechanisms can really replace laws at the heart of our thinking about science. In doing so, he enters a long-standing discussion about the relationship between the mech-anistic structures evident in the theories of contemporary biology and the laws of nature privileged especially in traditional empiricist traditions of the philosophy of science (see e.g. Wimsatt 1974; Bechtel and Abrahamsen 2005; Bogen 2005; Darden 2006; Glennan 1996; MDC 2000; Schaffner 1993; Tabery 2003; Weber 2005). In our view, Leuridan (...) misconstrues this discussion. His weak positive claim that mechanistic sciences appeal to generalizations is true but uninteresting. His stronger claim, that all causal claims require laws, is unsupported by his arguments. Though we proceed by criticizing Leuridan’s arguments, our greater purpose is to embellish his arguments in order to show how thinking about mechanisms enriches and transforms old philosophical debates about laws in biology and provides new insights into how generalizations afford prediction, explanation and control. (shrink)

The two purposes of this essay. The general philosophical problem with most versions of social libertarianism and how this essay will proceed. The specific problem with liberty explained by a thought-experiment. The positive and abstract theory of interpersonal liberty-in-itself as ‘the absence of interpersonal initiated constraints on want-satisfaction’, for short ‘no initiated impositions’. The individualistic liberty-maximisation theory solves the problems of clashes, defences, and rectifications without entailing interpersonal utility comparisons or libertarian consequentialism. The practical implications of instantiating liberty: three rules (...) of liberty-in-practice, 1) initial ultimate control of one’s body, 2) initial ultimate control of one’s used resources, 3) consensual interpersonal interactions and resource transfers. These rules are economically efficient and maximise general want-satisfaction. Private property and legal remedies are additional practical institutional aspects, but to which ‘initiated impositions’ then apply prima facie. Libertarian law is often mistaken for complete libertarianism. Moral explanations are a separate issue. The three main moral theories imply libertarianism, but it can be morally posited independently of them. Critical rationalism and its application. No empirical or argumentative support for theories. An important ambiguity with ‘justification’. How the epistemology applies to the theory of liberty and its application but remains separable in principle. Conclusion: there are further published explanations but this should be enough to generate useful criticism. Appendix replying to some typical comments. (shrink)

Schopenhauer repeatedly claims that all pleasure is negative, and this view seems to play key roles throughout his work. Nonetheless, many scholars have argued that Schopenhauer actually acknowledges certain positive pleasures. Two major arguments have been offered for this reading, one focused on the link between Schopenhauer's view of pleasure and Plato's, and one focused on Schopenhauer's distinction between two components of aesthetic pleasure. I argue that neither way of motivating the positive pleasure reading succeeds. Both overlook a key aspect (...) of Schopenhauer's account: namely, his suggestion that there are two distinct kinds of negative pleasure, pleasures of satisfaction and pleasures of distraction. When Schopenhauer claims that all pleasure is negative, he means it. (shrink)

One finds, in Maxwell's writings on thermodynamics and statistical physics, a conception of the nature of these subjects that differs in interesting ways from the way that they are usually conceived. In particular, though—in agreement with the currently accepted view—Maxwell maintains that the second law of thermodynamics, as originally conceived, cannot be strictly true, the replacement he proposes is different from the version accepted by most physicists today. The modification of the second law accepted by most physicists is a probabilistic (...) one: although statistical fluctuations will result in occasional spontaneous differences in temperature or pressure, there is no way to predictably and reliably harness these to produce large violations of the original version of the second law. Maxwell advocates a version of the second law that is strictly weaker; the validity of even this probabilistic version is of limited scope, limited to situations in which we are dealing with large numbers of molecules en masse and have no ability to manipulate individual molecules. Connected with this is his concept of the thermodynamic concepts of heat, work, and entropy; on the Maxwellian view, these are concepts that must be relativized to the means we have available for gathering information about and manipulating physical systems. The Maxwellian view is one that deserves serious consideration in discussions of the foundation of statistical mechanics. It has relevance for the project of recovering thermodynamics from statistical mechanics because, in such a project, it matters which version of the second law we are trying to recover. (shrink)

Neo-Humean instrumentalists hold that anagent's reasons for acting are grounded in theagent's desires. Numerous objections have beenleveled against this view, but the mostcompelling concerns the problem of ``aliendesires'' – desires with which the agent doesnot identify. The standard version ofneo-Humeanism holds that these desires, likeany others, generate reasons for acting. Avariant of neo-Humeanism that grounds anagent's reasons on her values, rather than allof her desires, avoids this implication, but atthe cost of denying that we have reasons to acton innocent whims. (...) A version of neo-Humeanismthat holds that an agent has reason to satisfyall of her desires that are not in conflictwith her values appears to allow us to grantthe reason-giving force of innocent whims whiledenying the reason-giving force of alien desires. (shrink)

This article discusses the adequacy of Rawls’ theory of justice as a tool for racial justice. It is argued that critics like Charles W Mills fail to appreciate both the insights and limits of the Rawlsian framework. The article has two main parts spread out over several different sections. The first is concerned with whether the Rawlsian framework suffices to prevent racial injustice. It is argued that there are reasons to doubt whether it does. The second part is concerned with (...) whether a Rawlsian framework has the resources to rectify past racial injustice. It is argued that it has more resources to do this than Mills allows. This second part of the article centers on two Rawlsian ideas: ideal theory and the fair equality of opportunity principle. It is argued that ideal theory is essential for the kind of rectificatory work that Mills wants nonideal theory to do, and that where there is a socioeconomic legacy of past injustice, it is hard to see how FEO could be implemented if it did no rectificatory work, a result which means that there is less need to turn to nonideal theory at all. (shrink)

This article argues that a person’s well-being at a time and the goodness of her life are two distinct values. It is commonly accepted as platitudinous that well-being is what makes a life good for the person who lives it. Even philosophers who distinguish between well-being at a time and the goodness of a life still typically assume that increasing a person’s well-being at some particular moment, all else equal, necessarily improves her life on the whole. I develop a precise (...) statement of this standard assumption, and then show that it is subject to counterexamples. The possibility of such counterexamples depends only on premises similar to those sometimes invoked to argue that a person’s well-being over a long period is not simply the aggregate well-being of the shorter periods that compose the long period. The refutation of the standard assumption linking well-being and life-goodness entails that these are distinct and sometimes divergent values. As an alternative to the standard assumption, it is proposed that well-being is best understood as an ingredient in a good life. (shrink)

Classically, gratitude is a tri-polar construal, logically ordering a benefactor, a benefice, and a beneficiary in a favour-giving-receiving situation. Grammatically, the poles are distinguished and bound together by the prepositions ”to’ and ”for’; so I call this classic concept ”to-for’ gratitude. Classic religious gratitude follows this schema, with God as the benefactor. Such gratitude, when felt, is a religious experience, and a reliable readiness or ”habit’ of such construal is a religious virtue. However, atheists have sometimes felt an urge or (...) need for an analogous experience and virtue of gratitude, and theists sometimes feel intellectual discomfort with classical theistic gratitude on consideration of the misfortunes that characterize our life along with its blessings. In response, another conception of religious gratitude has been attempted, a construal that lacks the to-for structure. This paper probes the significance of the benefactor for gratitude, both secular and religious, and, with Søren Kierkegaard’s help, some features of the theology of classical religious gratitude that dissolve the problem of misfortunes. (shrink)

We consider an ethical dilemma in global health: is it ethically acceptable to provide some patients cheaper treatments that are less effective or more toxic than the treatments other patients receive? We argue that it is ethical to consider local resource constraints when deciding what interventions to provide. The provision of cheaper, less effective health care is frequently the most effective way of promoting health and realizing the ethical values of utility, equality, and priority to the worst off.

Government’s use of imprisonment raises distinctive moral issues. Even if government has broad authority to make and to enforce law, government may not be entitled to use imprisonment as a punishment for all the criminal laws it is entitled to make. Indeed, there may be some serious crimes that it is wrong to punish with imprisonment, even if the conditions of imprisonment are humane and even if no adequate alternative punishments are available.

In this article, we explore the implications of opposing domains theory for developing ethical leaders. Opposing domains theory highlights a neurological tension between analytic reasoning and socioemotional reasoning. Specifically, when we engage in analytic reasoning, we suppress our ability to engage in socioemotional reasoning and vice versa. In this article, we bring together the domains of neuroscience, psychology, and ethics, to inform our theorizing around ethical leadership. We propose that a key issue for ethical leadership is achieving a healthy balance (...) between analytic reasoning and socioemotional reasoning. We argue that organizational culture often encourages too heavy a reliance on nonemotional forms of reasoning to arrive at moral judgments. As a result, leaders run the risk of suppressing their ability to pay attention to the human side of moral dilemmas and, in doing so, dehumanize colleagues, particularly subordinates, and clients. (shrink)

A common view among nontheists combines the de jure objection that theism is epistemically unacceptable with agnosticism about the de facto objection that theism is false. Following Plantinga, we can call this a “proper” de jure objection—a de jure objection that does not depend on any de facto objection. In his Warranted Christian Belief, Plantinga has produced a general argument against all proper de jure objections. Here I first show that this argument is logically fallacious (it makes subtle probabilistic fallacies (...) disguised by scope ambiguities), and proceed to lay the groundwork for the construction of actual proper de jure objections. (shrink)

Grete Hermann’s essay “Die naturphilosophischen Grundlagen der Quantenmechanik” has received much deserved scholarly attention in recent years. In this paper, I follow the lead of Elise Crull who sees in Hermann’s work the general outlines of a neo-Kantian interpretation of quantum theory. In full support of this view, I focus on Hermann’s central claim that limited spatio-temporal, and even analogically causal, representations of events exist within an overall relational structure of entangled quantum mechanical states that defy any unified spatio-temporal description. (...) In my view, Hermann also advances an important transcendental argument that perspectival spatio-temporal representations of nature have their foundations in general relational networks that are not spatio-temporal. The key point is that the adoption of a perspectival system within the general network induces the representation but only for that context. These ideas are consistent with a perspectival subject–object principle in Kant and also with Weyl’s work on Lie groups and their representations. (shrink)

Almost all philosophers agree that a necessary condition on lying is that one says what one believes to be false. But, philosophers haven’t considered the possibility that the true requirement on lying concerns, rather, one’s degree-of-belief. Liars impose a risk on their audience. The greater the liar’s confidence that what she asserts is false, the greater the risk she’ll think she’s imposing on the dupe, and, therefore, the greater her blameworthiness. From this, I arrive at a dilemma: either the belief (...) requirement is wrong, or lying isn’t interesting. I suggest an alternative necessary condition for lying on a degree-of-belief framework. (shrink)

The problem of moral disagreement has been presented as an objection to contextualist semantics for ‘ought’, since it is not clear that contextualism can accommodate or give a convincing gloss of such disagreement. I argue that independently of our semantics, disagreements over ‘ought’ in non-cooperative contexts are best understood as indirect metalinguistic disputes, which is easily accommodated by contextualism. If this is correct, then rather than posing a problem for contextualism, the data from moral disagreements provides some reason to adopt (...) a semantics that allows contextual variance in the meanings of ‘ought’. (shrink)

I argue that the offense generation pattern of slurring terms parallels that of impoliteness behaviors, and is best explained by appeal to similar purely pragmatic mechanisms. In choosing to use a slurring term rather than its neutral counterpart, the speaker signals that she endorses the term. Such an endorsement warrants offense, and consequently slurs generate offense whenever a speaker's use demonstrates a contrastive preference for the slurring term. Since this explanation comes at low theoretical cost and imposes few constraints on (...) an account of the semantics of slurs, this suggests that we should not require semantic accounts to provide an independent explanation of the offense profile. (shrink)

This is a response to Macleod 2012's argument that the history of unjust property acquisitions requires rich libertarians to give away everything in excess of equality. At first, problematic questions are raised. How much property is usually inherited or illegitimate? Why should legitimate inheritance be affected? What of the burden of proof and court cases? A counterfactual problem is addressed. Three important cases are considered: great earned wealth; American slavery; land usurpation. All are argued to be problematic for Macleod 2012's (...) thesis. Various problems are explained concerning using the Nozickian argument to decide the alleged excess that rich libertarians own. The essay's main error is the presupposition that free markets do not help the worst-off. The majority of unjust holdings today are not the result of historical injustices but arise through continuing transfers enabled by taxation and state-regulation. More study of libertarian contributions to the social sciences and philosophy would appear to be desirable "personal behavior" among socialists. (shrink)

It is often assumed that trolling is an intentional action. The aim of the paper is to argue for a form of unintentional trolling. Firstly, we outline minimal conditions for intentional actions. Secondly, an unintentional trolling example is introduced. Thirdly, we will show that in some cases, an utterance can be expressive, while it is perceived as descriptive. On the basis of the justification-suppression model, we argue that the introduced trolling example is such a case. In order to bypass social (...) sanctions for expressing prejudices, agents unintentionally express their prejudices through stories that appear to be descriptive. Thereby, the characterized behavior does not fulfill the minimal conditions for intentional action. Fourthly, we give criteria that can be used to identify unintentional trolls. Finally, after unintentional trolling is analyzed, the trolls’ behavioral goals are considered. In conclusion, an analysis of unintentional trolling is given, which has explanatory benefits in contrast to the classic intentional trolling concepts. (shrink)

The paper proposes a new technique for dealing with multi-attribute decision making problems through an extended TOPSIS method under neutrosophic cubic environment. Neutrosophic cubic set is the generalized form of cubic set and is the hybridization of a neutrosophic set with an interval neutrosophic set. In this study, we have defined some operation rules for neutrosophic cubic sets and proposed the Euclidean distance between neutrosophic cubic sets. In the decision making situation, the rating of alternatives with respect to some predefined (...) attributes are presented in terms of neutrosophic cubic information where weights of the attributes are completely unknown. In the selection process, neutrosophic cubic positive and negative ideal solutions have been defined. An extended TOPSIS method is then proposed for ranking the alternatives and finally choosing the best one. Lastly, an illustrative example is solved to demonstrate the decision making procedure and effectiveness of the developed approach. (shrink)

In this paper, I argue that no strong doctrine of the Fall can undermine the propriety of epistemic self-trust. My argument proceeds by introducing a common type of philosophical methodology, known as reflective equilibrium. After a brief exposition of the method, I introduce a puzzle for someone engaged in the project of self-reflection after gaining a reason to distrust their epistemic selves on the basis of a construal of a doctrine of the Fall. I close by introducing the worry as (...) a formal argument and demonstrate the self-undermining nature of such an argument. (shrink)

In addition to protecting agents’ autonomy, consent plays a crucial social role: it enables agents to secure partners in valuable interactions that would be prohibitively morally risk otherwise. To do this, consent must be observable: agents must be able to track the facts about whether they have received a consent-based permission. I argue that this morally justifies a consent-practice on which communicating that one consents is sufficient for consent, but also generates robust constraints on what sorts of behaviors can be (...) taken as consent- communicating. (shrink)

Goldman, though still a reliabilist, has made some recent concessions to evidentialist epistemologies. I agree that reliabilism is most plausible when it incorporates certain evidentialist elements, but I try to minimize the evidentialist component. I argue that fewer beliefs require evidence than Goldman thinks, that Goldman should construe evidential fit in process reliabilist terms, rather than the way he does, and that this process reliabilist understanding of evidence illuminates such important epistemological concepts as propositional justification, ex ante justification, and defeat.

The relation between Hume’s constructive and skeptical aims has been a central concern for Hume interpreters. Hume’s two definitions of ‘cause’ in the Treatise and first Enquiry apparently represent an important constructive achievement, but this paper argues that the definitions must be understood in terms of Hume’s skepticism. The puzzle I address is simply that Hume gives two definitions rather than one. I use Don Garrett’s interpretation as a foil to develop my alternative skeptical interpretation. Garrett claims the definitions exhibit (...) a general susceptibility to two kinds of definition that all “sense-based concepts” share. Against Garrett, I argue that the definitions express an imperfection Hume finds only in our concept of causation. That imperfection is absent from other sense-based concepts, and prompts skeptical sentiments in Hume’s conclusion to the Treatise’s Book 1. I close by comparing my interpretation with those of Helen Beebee, Stephen Buckle, Galen Strawson and Paul Russell. (shrink)

“Critical-Rationalist Libertarianism” (CRL) was replied to in “Libertarianism Without Argument” (the reply). Various points in that text are here given responses. Both critical rationalism and how it applies to libertarianism are elucidated and elaborated. This response will proceed by quoting the reply where relevant (virtually all of it) and then responding immediately after the quotations, following the order of the reply’s very brief “critique” (605 words).

In _Leviathan_, Hobbes embraces three seemingly inconsistent claims: (i) the unity of a multitude is secured only by the unity of its representer, (ii) assemblies can represent other multitudes, and (iii) assemblies are, or are constituted by, multitudes. Together these claims require that a representative assembly, itself, be represented. If that representer is another assembly, it too will need a unifying representer, and so on. To stop a regress, we will need an already unified representer. But a multitude can only (...) speak or act through its representer, and an assembly is a multitude, so any representing done by the assembly is actually done by this already unified, regress-stopping representer. That is, if (i) and (iii) are true, (ii) cannot be. I will argue that this inconsistency is only apparent and that we can resolve it without rejecting any of these three claims. We do this by appealing to a representer-as-decision-procedure meeting certain criteria. Such a procedural representer breaks the transitivity of representation such that the assembly it represents can properly represent some further multitude. I proceed in my defense of the procedural representer view by addressing a series of problems it faces, the solutions to which give us a progressively clearer picture of the criteria this representer must meet. (shrink)

While it is often said that robotics should aspire to reproducible and measurable results that allow benchmarking, I argue that a focus on benchmarking can be a hindrance for progress in robotics. The reason is what I call the ‘measure-target confusion’, the confusion between a measure of progress and the target of progress. Progress on a benchmark (the measure) is not identical to scientific or technological progress (the target). In the past, several academic disciplines have been led into pursuing only (...) reproducible and measurable ‘scientific’ results – robotics should be careful to follow that line because results that can be benchmarked must be specific and context-dependent, but robotics targets whole complex systems for a broad variety of contexts. While it is extremely valuable to improve benchmarks to reduce the distance be- tween measure and target, the general problem to measure progress towards more intelligent machines (the target) will not be solved by benchmarks alone; we need a balanced approach with sophisticated benchmarks, plus real-life testing, plus qualitative judgment. (shrink)

The link between human nature and human flourishing is undeniable. "A healthy tree cannot bear bad fruit, nor can a diseased tree bear good fruit" (Matt. 7:18). The ontology of the human person will, therefore, ground the nature of human flourishing and thereby sanctification. Spiritual formation is the area of Christian theology that studies sanctification, the Spirit-guided process whereby disciples of Jesus are formed into the image of Jesus (Rom. 8:28-29; 2 Cor. 3:18; 2 Peter 3:18). Until the nineteenth century, (...) there was an overwhelming consensus among Christian thinkers that some form of mind-body (or soul-body) dualism is true of human beings. Recently, that consensus has eroded, and with it the availability of a shared body of knowledge about spiritual formation. Some Christian physicalists argue that dualism is incompatible with central elements of spiritual formation. Neuroscientist Warren Brown and psychologist Brad Strawn offer the only substantive account of spiritual formation from the view of Christian physicalism and its accompanying objections to dualism. It is on their arguments that this chapter focuses. We argue that Brown and Strawn fail to support their incompatibility thesis. Additionally, we argue that Christian physicalism stands in tension with important philosophical and theological foundations of Christian spiritual formation. In doing so we offer a specific form of dualism, the bodily soul view, and explain how this view illuminates the importance of embodiment, our neurological and social development, and hence the important physical aspects of Christian spiritual formation. (shrink)

Arguments for handgun ownership typically appeal to handguns’ value as an effective means of self-protection. Against this, critics argue that private ownership of handguns leads to more social harm than it prevents. Both sides make powerful arguments, and in the absence of a reasonable consensus regarding the merits of gun ownership, David DeGrazia proposes two gun control policies that ‘reasonable disputants on both sides of the issue have principled reasons to accept.’ These policies hinge on his claim that ‘an even-handed (...) examination of the available evidence casts considerable doubt on the thesis that handgun ownership enables more adequate self-defense and physical security in the home.’ We challenge DeGrazia’s ‘moderate gun control’ policies on both philosophical and empirical grounds. Philosophically, we show that the arguments he gives in support of his proposed gun-control measures are too narrow and incomplete to warrant his conclusions about what kind of gun control there ought to be, even if he is right about the empirical evidence. Empirically, we argue that a truly even-handed examination of the evidence makes DeGrazia’s claim that gun ownership is on average self-defeating much less plausible than he supposes. Our conclusion is that DeGrazia has failed to establish his claim that gun ownership is self-defeating and therefore has no case for the gun-control policies he suggests. (shrink)

The problem analysed in this paper is whether we can gain knowledge by using valid inferences, and how we can explain this process from a model-theoretic perspective. According to the paradox of inference (Cohen & Nagel 1936/1998, 173), it is logically impossible for an inference to be both valid and its conclusion to possess novelty with respect to the premises. I argue in this paper that valid inference has an epistemic significance, i.e., it can be used by an agent to (...) enlarge his knowledge, and this significance can be accounted in model-theoretic terms. I will argue first that the paradox is based on an equivocation, namely, it arises because logical containment, i.e., logical implication, is identified with epistemological containment, i.e., the knowledge of the premises entails the knowledge of the conclusion. Second, I will argue that a truth-conditional theory of meaning has the necessary resources to explain the epistemic significance of valid inferences. I will explain this epistemic significance starting from Carnap’s semantic theory of meaning and Tarski’s notion of satisfaction. In this way I will counter (Prawitz 2012b)’s claim that a truth-conditional theory of meaning is not able to account the legitimacy of valid inferences, i.e., their epistemic significance. (shrink)